How to Make CBD and CBG Topicals for Targeted Pain Relief

The Skin’s Endocannabinoid System (ECS)

Your skin is a sensory organ packed with CB1 and CB2 receptors. These receptors serve as gatekeepers for pain signals and inflammatory responses. When you apply a cannabinoid-infused balm, the compounds may bind to these receptors to help quiet overactive nerves and calm irritated tissue. Many users report a "quieting" sensation within 15 to 20 minutes of application.

Cannabinoid Selection: CBD vs. CBG

The effectiveness of a salve depends on the specific cannabinoids chosen. CBD (Cannabidiol) is often used for inflammation. It may work by inhibiting pro-inflammatory cytokines, which is why it is frequently utilized for discomfort associated with arthritis, joint pain, and post-workout recovery.

CBG (Cannabigerol) acts differently. As a precursor to other cannabinoids, it may support skin-cell regeneration. CBG stimulates natural lipid production, helping your skin retain moisture. If you are managing chronic dry skin or minor abrasions, CBG may be a beneficial addition to your routine.

Pro-tip: A 1:1 ratio of CBD to CBG hits a balanced range, as it may address underlying inflammation while supporting the skin barrier.

The Role of Beta-Caryophyllene

While most essential oils are used for scent, Beta-Caryophyllene (BCP) is a functional ingredient. It is one of the few plant terpenes that acts as a dietary cannabinoid by binding to CB2 receptors.

Adding BCP to your topical may increase the skin’s permeability, helping the CBD and CBG reach deeper dermal layers. It also provides a local effect that may interrupt pain signals upon contact.

Selecting the Right Carrier Medium

The carrier oil dictates how deeply the cannabinoids travel and how the product feels on your skin.

• For Deep Tissue: Use Jojoba or MCT oil. These have small molecular structures that penetrate the skin quickly without leaving a greasy residue.
• For Surface Protection: Use Shea butter or Beeswax. These act as occlusives, creating a protective seal that keeps the cannabinoids in contact with a rash, burn, or surface irritation for longer periods.

Recipe: Maximum Relief CBG/CBD Cooling Salve

This formulation balances rapid absorption with a long-lasting protective barrier.

Ingredients

• 1 cup Infused Jojoba Oil: Use a 1:1 ratio of decarboxylated CBD and CBG flower.
• 1/4 cup Beeswax Pastilles: For structure and protection.
• 2 tbsp Menthol Crystals: For a cooling sensation.
• 1 tsp Vitamin E Oil: A natural preservative to help prevent oxidation.
• 15 drops Beta-Caryophyllene: For enhanced absorption and analgesic properties.

Step-by-Step Instructions

1. Decarboxylation: Bake your hemp flower at 240°F (115°C). CBD flower takes about 40 minutes. CBG flower is more delicate—keep it to 30 to 35 minutes.
2. Infusion: Combine the flower and Jojoba oil in a double boiler. Keep it at 160°F for 4 hours, then strain through fine cheesecloth.
3. Melting: Heat your infused oil and beeswax together until the mixture is completely clear.
4. Temperature Control: Remove from heat and let it cool to 120°F. Adding menthol and terpenes while the mixture is boiling hot may cause them to evaporate, reducing their effectiveness.
5. Setting: Stir in the Vitamin E, menthol, and BCP. Pour into dark amber glass jars—the dark glass helps protect your cannabinoids from degrading in UV light.

Safety and Stability Standards

Watch the Water

If you add water-based ingredients like aloe vera or tea, you introduce mold risks. If you use water, keep the jar in the fridge and finish it within 30 days. Stick to oil-only balms for a longer shelf life.

pH Balance

Your skin is naturally acidic (pH 4.5 to 5.5). Many DIY balms are too alkaline, which may cause irritation. A tiny pinch of citric acid can help match your skin’s pH.

Potency Math

Calculate your dosage accurately. If you use 10 grams of flower at 20% CBD content, you start with 2,000mg. Subtract roughly 20% for the loss that occurs during infusion, giving you about 1,600mg in the final batch. Divide that by the total ounces to find your mg-per-ounce.

Sourcing

Professional results start with quality genetics. Look for White CBG strains for repair or high-myrcene CBD strains for relaxation. Matching your flower’s terpene profile to your specific goal may help improve the quality of your personal wellness preparations.

---

Legal Disclaimer: This content is for educational and informational purposes only and does not constitute medical advice. Always seek the advice of a physician regarding a medical condition. Efficacy has not been confirmed by FDA-approved research. Check your local laws regarding cannabis and terpene use.

Sources

1. Bíró T, Tóth BI, Haskó G, Pacher P, Pál J. (2009). The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities. Trends Pharmacol Sci. 30(8):411-20. PubMed

2. Hammell DC, Zhang LP, Ma F, Abshire SM, McIlwrath SL, Stinchcomb AL, Westlund KN. (2016). Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. Eur J Pain. 20(6):936-48. PubMed

3. Russo EB. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 163(7):1344-64. PubMed

4. Gertsch J, Leonti M, Raduner S, Racz I, Chen JZ, Xie XQ, Altmann KH, Karsak M, Zimmer A. (2008). Beta-caryophyllene is a dietary cannabinoid. Proc Natl Acad Sci USA. 105(26):9099-104. PubMed

5. Navarro G, Varani K, Reyes-Resina I, Sánchez de Medina V, Rivas-Santisteban R, Sánchez-Carnerero Callado C, Borges F, Borea PA, Pardo L, Franco R. (2018). Cannabigerol action at cannabinoid CB1 and CB2 receptors and at CB1-CB2 heteroreceptor complexes. Front Pharmacol. 9:632. PubMed