Indica Strains

Why indicas tend to sedate

Indica-leaning chemotypes are typically Myrcene-dominant. Myrcene is the most abundant terpene in cannabis and produces a sedating, couch-lock quality by potentiating CB1 receptor activity and interacting with GABA receptors in a way that resembles the sedative mechanism of benzodiazepines. High Myrcene content (>0.5% in flower) is the single strongest predictor of a sedating, body-heavy experience.

Pain relief and the indica association

Beta-Caryophyllene — the only terpene that directly activates CB2 receptors — is also common in indica-leaning strains. CB2 activation modulates peripheral pain and inflammation without the psychoactive effects of CB1 activation. Combined with Linalool (anxiolytic, analgesic) and Myrcene, this makes many indicas effective for body pain, muscle tension, and inflammation.

Best use cases

Evening relaxation, sleep support, chronic pain, muscle soreness, anxiety relief, and appetite stimulation. Avoid for daytime productivity — the sedating terpene profile is counterproductive for focus-oriented work.

Signature Terpenes

Common Effects

Indica Strains in Our Database

50 strains · click any for full profile